Positively Aware Tivicay


dolutegravir DTG (INSTI)

DHHS recommended as a component of initial regimen for most people
Integrase Inhibitor

Standard Dose

One 50 mg tablet once daily, with or without food, for individuals on HIV therapy for the first time (treatment-naïve) or treatment-experienced individuals who have never had treatment failure with an INSTI. One 50 mg tablet twice daily, with or without food, for adults who have or who are suspected of having certain INSTI drug resistance or who are taking certain other medications. Must be taken in combination with another antiretroviral(s) from a different drug class.

For adults and children weighing more than 44 pounds (20 kg), use standard dose listed above or see package labeling. Tivicay PD tablets (5 mg), taken with or without food, are dispersible in water (oral suspension) for pediatric patients age four weeks and older weighing at least 6.6 pounds (3 kg). Children weighing at least 30.8 pounds (14 kg) may take either Tivicay or Tivicay PD, but Tivicay PD is preferred for those weighing between 30.8 to 44 lbs. Dosing under 44 lbs is weight-based; Tivicay is also available in 10 mg and 25 mg tablets. Do not chew, cut, or crush Tivicay PD tablets. If dose is more than one Tivicay PD tablet, swallow one tablet at a time. If using a dispersible dose, see package insert for mixing instructions. Dosing of Tivicay and Tivicay PD for oral suspension cannot be interchanged on a milligram per milligram basis.

Take missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose. Not recommended for people with severe liver impairment. Use with caution in people with severe kidney impairment who have INSTI drug resistance or suspected resistance, because Tivicay levels may be decreased.
  • See package insert for more complete information on potential side effects and interactions.


ViiV Healthcare
viivhealthcare.com; tivicay.com
(877) 844-8872


50 mg tablets: $2,557.03/month

Potential Side Effects and Toxicity

Potential Drug Interactions

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