Genvoya and Stribild

elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide EVG/COBI/FTC/TAF and elvitegravir/cobicistat/emtricitabine/tenofovir disoproxil fumarate EVG/COBI/FTC/TDF

Recommended initial regimens in certain clinical situations
Single-Tablet Regimen

Standard Dose

One tablet once daily with food. For people taking HIV treatment for the first time (treatment-naïve) or individuals with suppressed viral load on a stable HIV regimen for at least 6 months who have no known resistance to the elvitegravir, emtricitabine, or tenofovir components of the regimen. Tablets contain 150 mg of the INSTI elvitegravir boosted by 150 mg cobicistat plus 200 mg emtricitabine, with 10 mg TAF in Genvoya and 300 mg TDF in Stribild.

Genvoya: For adults and children weighing at least 55 pounds (25 kg) and having a creatinine clearance (CrCl) of at least 30 mL/min (measurement of kidney function), as well as adults with creatinine clearance below 15 mL/min who are receiving chronic hemodialysis (HD). For people on chronic hemodialysis, take tablet once daily and administer after completion of hemodialysis on days of HD treatment. Dose cannot be adjusted for people with liver problems. Genvoya is not recommended for people who have severe liver problems, a CrCl between 15–30 mL/min, or a CrCl less than 15 mL/min who are not receiving chronic hemodialysis.

Stribild: For adults and children age 12 and older weighing at least 77 pounds (35 kg). Dose cannot be adjusted for people with kidney or liver problems. Stribild should not be started by individuals with estimated CrCl less than 70 mL/min and should be discontinued if CrCl decreases to less than 50 mL/min.

Take missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose.
  • See the individual drugs: Emtriva, Viread, and Tybost. Elvitegravir is not available separately. TAF is not available separately for HIV, but is used to treat hepatitis B under the brand name Vemlidy.
  • See package insert for more complete information on potential side effects and interactions.

Manufacturer

Gilead Sciences, Inc.
gilead.com; genvoya.com
(800) GILEAD-5 (445-3235)

AWP

Genvoya
$4,300.56/month

Stribild
$4,511.29/month

Potential Side Effects and Toxicity

Potential Drug Interactions

More Information

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