Symtuza pill image


DRV/COBI/FTC/TAF darunavir/cobicistat/emtricitabine/tenofovir alafenamide

Recommended initial regimen in certain clinical situations
Single-Tablet Regimen

Standard Dose

One tablet once daily with food for treatment-naïve people or people with suppressed viral load on a stable HIV regimen for at least 6 months who have no known resistance to the darunavir or tenofovir components of the regimen. Tablet contains 800 mg darunavir, 150 mg cobicistat, 200 mg emtricitabine, and 10 mg tenofovir alafenamide.

Take missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose. Dose cannot be adjusted for people with kidney or liver problems. Symtuza can be used in people with an estimated creatinine clearance of at least 30 mL/ min. It should not be used in people with severe kidney or liver impairment.

See the individual drugs contained in Symtuza: Prezista, Tybost, and Descovy.

See package insert for more complete information on potential side effects and interactions.


Janssen Therapeutics
(800) JANSSEN (526-7736)



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