Positively Aware Mavyret


glecaprevir/pibrentasvir (GLE/PIB)

FDA approved for HIV/HCV co-infection.
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Standard Dose

Three tablets once daily with food in adults and children weighing at least 45 kg. Each tablet contains 100 mg of glecaprevir and 40 mg of pibrentasvir for a total daily dose of 300 mg/120 mg. It is important to take all three tablets at the same time—do not separate throughout the day. See treatment duration tables below. The number of weeks on treatment depends on such things as cirrhosis status and previous therapy. New oral pellet formula was approved in June 2021, which now allows dosing in children ages 3 and older, without cirrhosis or with compensated cirrhosis, based on weight.

Take your missed dose as soon as possible unless it is less than 12 hours until your next dose. Do not double up on your next dose.




100 40 mg tablets: $15,840 / month
3–6 packets/day of 50/20 mg packets: $9,505–$19,009 / month

Potential Side Effects and Toxicity

Potential Drug Interactions

More Information