Guest Editors' Note
![Guest Editors David Evans and Richard Jefferys Guest Editors David Evans and Richard Jefferys](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/guest-editors-note-900x600px-v2.jpg?itok=QNkMYeqy)
Guest Editors' Note Winter 2017/2018
Handle with care: Speaking the language of an HIV cure
Front Cover Back Story
![The co-creator and star of the web series Merce envisions life with an HIV cure The co-creator and star of the web series Merce envisions life with an HIV cure](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/keep-hope-alive-2400x800px.jpg?itok=mVy4g81a)
It's important that we keep hope alive
The co-creator and star of the web series Merce envisions life with an HIV cure
Features
![The challenge of defining an HIV cure The challenge of defining an HIV cure](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/The-challenge-of-defining-2400x800px.jpg?itok=F0MqsmTb)
The challenge of defining an HIV cure
Different roads to the holy grail
![Measuring the HIV reservoir Measuring the HIV reservoir](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/measuring-the-reservoir-2400x800px.jpg?itok=QZfUhh_V)
Measuring the HIV reservoir
Current tests for sizing up viral hideouts
![New strategies target dormant HIV New strategies target dormant HIV](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/latent-tendencies-v2-900x600px.jpg?itok=p720mJEH)
Latent tendencies
New strategies target dormant HIV
![Manipulating the immune system to tackle HIV Manipulating the immune system to tackle HIV](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/enhancing-immunity-2400x800px.jpg?itok=-67K6xbb)
Enhancing immunity
Manipulating the immune system to tackle HIV
![Collaborating on a cure Collaborating on a cure](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/collaborating-on-a-cure-2400x800px.jpg?itok=Kgsfyj3G)
Collaborating for a cure
Six groups focused on the task
![Modifying immune system cells to resist, attack, or remove HIV altogether Modifying immune system cells to resist, attack, or remove HIV altogether](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/gene-therapy-900x600px.jpg?itok=GkI9sE6y)
Gene therapy in HIV cure research
Modifying immune system cells to resist, attack, or remove HIV altogether
![Treatment interruption: A risky but essential step in cure research Treatment interruption: A risky but essential step in cure research](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/time-out-2400x800px.jpg?itok=2PwhhHlL)
Time out
Treatment interruption: A risky but essential step in cure research
![Advocate Michael Louella talks about ‘50 shades of cure’ Advocate Michael Louella talks about ‘50 shades of cure’](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/speaking-the-same-language-2400x800px.jpg?itok=GGR7SFNn)
Speaking the same language
Advocate Michael Louella talks about ‘50 shades of cure’
![Four individuals share their hopes and fears Four individuals share their hopes and fears](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/what-a-cure-means-to-you-2400x800px.jpg?itok=ASRnKMcp)
What does a cure mean to you?
Four individuals share their hopes and fears
![Pioneering scientists prove women are essential to finding a cure Pioneering scientists prove women are essential to finding a cure](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/better-late-than-never-2400x800px.jpg?itok=hKVjVk3m)
Better late than never
Pioneering scientists prove women are essential to finding a cure
![Bringing HIV Cure Research into the Real World Bringing HIV Cure Research into the Real World](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/into-the-real-world-2400x800px.jpg?itok=bQ7f5LWj)
Bringing HIV cure research into the real world
Looking at the need for including social science
Online Extra
![Paula Cannon in the lab Paula Cannon in the lab](https://www.positivelyaware.com/sites/default/files/styles/thumbnail_3_2/public/images/paulainlab.jpg?itok=-Av43m9c)
Q & A with Paula Cannon
A leading researcher’s take on gene therapy in HIV cure research