Positively Aware Truvada

Truvada

FTC/TDF emtricitabine/tenofovir disoproxil fumarate

Recommended as a component of initial regimen for most people
Nucleoside "Nuke"

Standard Dose

One tablet once daily without regard to food for adults and children weighing at least 77 pounds (35 kg). In children weighing 37–76 pounds (17–34 kg), Truvada is dosed based on body weight. See package insert for weight-based dosing. Truvada tablets are available in the following emtricitabine/tenofovir DF (TDF) dosages: 100/150 mg tablets, 133/200 mg tablets, 167/250 mg tablets, and 200/300 mg tablets. Tablets can dissolve in water, grape juice, or orange juice with minor stirring and pressure from a spoon; however, no studies have been performed to evaluate the pharmacokinetics (PK) or stability of crushed vs. intact tablets. When used for HIV treatment, Truvada must be taken in combination with another antiretroviral(s) that does not contain the medications in this drug combination.

Take a missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose. The dosing frequency needs to be adjusted for people who have decreased kidney function. The dose of Truvada should be adjusted if CrCl is less than 50 mL/min and Truvada should not be used if CrCl is less than 30 mL/min (less than 60 mL/min if used for PrEP) or if you are on dialysis. Truvada was approved for HIV prevention (pre-exposure prophylaxis, or PrEP) in 2012; see “Truvada for PrEP” page.
  • See the individual drugs contained in Truvada: Viread and Emtriva.
  • See package insert for more complete information on potential side effects and interactions.

Manufacturer

Gilead Sciences, Inc.
gilead.com; truvada.com
(800) GILEAD-5 (445–3235)

AWP

$2,210.74/month
generic: $2,100.20/month

Potential Side Effects and Toxicity

Potential Drug Interactions

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