Positively Aware Truvada

Truvada

emtricitabine/tenofovir disoproxil fumarate (FTC/TDF)

Recommended as component of initial regimen for most people
Nucleoside "Nuke"

Standard Dose

One tablet once daily without regard to food for adults and children weighing at least 77 pounds. In children weighing 37–76 pounds, Truvada is dosed based on body weight. See package insert for weight-based dosing. Truvada tablets are available in the following emtricitabine/tenofovir DF dosages: 100/150 mg tablets, 133/200 mg tablets, 167/250 mg tablets, and 200/300 mg tablets. Tablets can disintegrate in water, grape juice, or orange juice with minor stirring and pressure from a spoon; however, no studies have been performed to evaluate the pharmacokinetics (PK) or stability of crushed vs. intact tablets. Must be taken in combination with another antiretroviral(s) which does not contain the medications in this drug or medication from the same drug class.

Take a missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose. The dosing frequency needs to be adjusted for people with decreased kidney function. The dose of Truvada should be adjusted if CrCl is less than 50 mL/min and Truvada should not be used if CrCl is less than 30mL/min or if you are on dialysis.

Manufacturer

Gilead Sciences, Inc.
gilead.com
truvada.com
(800) GILEAD-5 (445–3235)

AWP

$2,010.95/month;
Approved as generic; generic not yet commercially available

Potential Side Effects and Toxicity

Potential Drug Interactions

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