DRV darunavir

Recommended as a component of initial regimen in certain clinical situations
Protease Inhibitor

Standard Dose

One 800 mg tablet plus 100 mg Norvir or 150 mg Tybost once daily with food for treatment-naïve people (those taking HIV therapy for the first time) and treatment-experienced adults without Prezista-related resistance. One 600 mg tablet with 100 mg Norvir twice daily with food for pregnant women and those who have at least one Prezista-related resistance mutation. Prezista should always be taken with Norvir or Tybost. Must also be taken in combination with another antiretroviral(s) which does not contain this medication or medication from the same drug class.

For adults and children 3 years of age and older weighing at least 22 pounds (10 kg). Prezista for children is dosed based on weight. There are 75 mg and 150 mg tablets as well as an oral suspension (100 mg/mL) (strawberry cream flavor) available for children three and older and adults who can’t swallow pills.

Suspension needs to be taken with Norvir or Tybost, with food. Suspension should be shaken before each use and stored at room temperature. Do not refrigerate.

Take missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose.
  •  See package insert for more complete information on potential side effects and interactions.


Janssen Therapeutics; (800) JANSSEN (526-7736)


600 mg, 60 tablets: $2,214.23/month
800 mg, 30 tablets: $2,214.23/month

Potential Side Effects and Toxicity

Potential Drug Interactions

More Information

Doctor Comments

Activist Comments