rilpivirine/emtricitabine/tenofovir alafenamide (RPV/FTC/TAF)

Recommended initial regimen in certain clinical situations
Single-Tablet Regimen

Standard Dose

One tablet once daily, with a standard meal (more than 390 calories). See below. Tablet contains 25 mg of the NNRTI rilpivirine plus 200 mg emtricitabine and 25 mg tenofovir alafenamide (TAF).

Must be taken with a meal that you chew—not just nutritional drinks or protein shakes. Taking rilpivirine without food could result in a 40% decrease in drug absorption and may lead to resistance.

People taking HIV treatment for the first time must have an HIV RNA (viral load) of less than 100,000 copies/mL and a CD4 T-cell count of more than 200 cells/mm3 before starting Odefsey due to higher rates of virologic failure in these patients

For adults and children 12 years of age and older weighing at least 77 pounds (35 kg) and having a CrCl of at least 30 mL/min.

Take missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose.


Gilead Sciences, Inc.
(800) GILEAD-5 (445-3235)

Janssen Therapeutics
(800) JANSSEN (526-7736)



Potential Side Effects and Toxicity

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