Positively Aware Epzicom


abacavir/lamivudine (ABC/3TC)

Recommended as a component of initial regimen for most people when used in combination with dolutegravir (as Triumeq)
Nucleoside "Nuke"

Standard Dose

One tablet once daily, without regard to food. Tablet contains 600 mg abacavir and 300 mg lamivudine. Must be taken in combination with another antiretroviral(s) that do not contain the medications in this drug combination.

Approved for adults and children weighing 55 pounds (25 kg) or more. Take missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose. According to the drug label, Epzicom is not recommended for people with decreased kidney function (creatinine clearance less than 50 mL/min) due to lamivudine component, or those with moderate or severe liver impairment due to abacavir component. This medication combination, however, is often used in reduced renal function below 50 mL/min due to relatively minimal risk of lamivudine accumulation and side effects. In addition, alternative doses may be obtained by using the individual components of this medication as needed.
  • See the individual drugs contained in Epzicom: Epivir and Ziagen.
  • See package insert for more complete information on potential side effects and interactions.


ViiV Healthcare
viivhealthcare.com; epzicom.com
(877) 844-8872


generic: $1,395.05/month

Potential Side Effects and Toxicity

Potential Drug Interactions

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