Positively Aware Epzicom


abacavir/lamivudine (ABC/3TC)

Recommended as a component of initial regimen for most people when used in combination with dolutegravir (as Triumeq)
Nucleoside "Nuke"

Standard Dose

One tablet once daily, without regard to food. The tablet contains 600 mg abacavir and 300 mg lamivudine. It must be taken in combination with another antiretroviral(s) that does not contain the medications in this drug combination.

Take the missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose. Approved for adults and children weighing 55 pounds (25 kg) or more. According to the drug label, Epzicom is not recommended for those with decreased kidney function (creatinine clearance less than 50 mL/min) due to lamivudine component, or those with moderate or severe liver impairment due to abacavir component. This medication combination, however, is often used in the reduced renal function below 50, due to relatively minimal risk of lamivudine accumulation and side effects. In addition, alternative doses may be obtained by using the individual components of this medication as needed.

See the individual drugs contained in Epzicom: Epivir and Ziagen.

See package insert for more complete information on potential side effects and interactions.


ViiV Healthcare
(877) 844-8872


1,550.05/month; generic: $1,395.05/month

Potential Side Effects and Toxicity

Potential Drug Interactions

More Information

Doctor Comments

Activist Comments