Positively Aware Atripla


efavirenz/emtricitabine/tenofovir disoproxil fumarate EFV/FTC/TDF

Recommended initial regimen in certain clinical situations
Single-Tablet Regimen

Standard Dose

One tablet once daily on an empty stomach, preferably at bedtime (food can increase the risk of central nervous system, or CNS, side effects). Tablet contains 600 mg of the NNRTI efavirenz plus 200 mg emtricitabine and 300 mg tenofovir disoproxil fumarate (TDF).

For adults and children 12 years of age and older weighing at least 88 pounds (40 kg).

Take missed dose as soon as possible, unless it is closer to the time of your next dose. Do not double up on your next dose. Do not split or crush the tablet. Dose cannot be adjusted for people with kidney problems; Atripla should not be used in people with moderate or severe kidney or liver impairment. Atripla is not recommended for people with CrCl less than 50mL/min or individuals requiring dialysis.

Similar, but not exact, medications are available (see Symfi and Symfi Lo).
  • See the individual drugs contained in Atripla: Sustiva and Truvada (co-formulation of Emtriva and Viread).
  • See package insert for more complete information on potential side effects and interactions.


Bristol-Myers Squibb
bms.com; atripla.com
(800) 321-1335

Gilead Sciences, Inc.
gilead.com; (800) GILEAD-5 (445–3235)


Generic is available:

Potential Side Effects and Toxicity

Potential Drug Interactions

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